Pyridines and derivatives
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- (1)
- (1)
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Filtered Search Results
Medchemexpress LLC IRBP(651-670) human, mouse | 1977546-93-2 | 99.6% | 2107.32 | 25 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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IRBP(651-670) human, mouse | 1977546-93-2 | 99.6% | 2107.32 | 25 MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC (R)-5-((2,3-difluorobenzyl)thio)-7-((1-hydroxypropan-2-yl)amino)thiazolo[4,5-d]pyrimidin-2(3H)-one | 333742-48-6 | 100.0% | 5 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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AZD8309 is an orally active small-molecule antagonist of the C-X-C chemokine receptor 2 (CXCR2), used as a research tool to modulate neutrophil transmigration and investigate inflammatory disease mechanisms.
- Orally active CXCR2 antagonist for in vitro and in vivo studies.
- Useful for studying neutrophil transmigration and inflammation pathways.
- Available in small research quantities (5 mg solid) and DMSO solution formats.
- Molecular weight 384.42 g·mol⁻¹; molecular formula C15H14F2N4O2S2.
- Provided as a research-grade compound for laboratory use only.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC AKB-6899 | 1007377-55-0 | 99.9% | 290.25 | 25 MG
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AKB-6899, a prolyl hydroxylase domain 3 (PHD3) inhibitor, is a selective HIF-2α stabilizer. It also increases soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated macrophages, and has antitumor and antiangiogenic effects.
- PHD3 inhibitor
- Selective HIF-2α stabilizer
- Increases soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated macrophages
- Has antitumor effects
- Has antiangiogenic effects
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Medchemexpress LLC CH1055 1MG | 1622250-38-7 | 94.2% | 969.09 | 1 MG
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CH1055 is a near-infrared II (NIR-II) fluorescent dye, suitable for use as a fluorescent probe in in vivo imaging applications. It can be conjugated with antibodies or ligands for specific imaging, such as tumor imaging.
- Much smaller than the renal excretion threshold
- Easily excreted from the body through the kidneys
- Reduces toxicity risk from long-term accumulation
- Excitation wavelength of 808 nM
- Emission wavelength of 1055 nM
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Medchemexpress LLC Seladelpar | 851528-79-5 | 99.75% | 444.46 | 25 MG
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Seladelpar | 851528-79-5 | 99.75% | 444.46 | 25 MG
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Medchemexpress LLC 5-amino-3-(4-phenoxyphenyl)-1-[(3r)-1-prop-2-enoylpiperidin-3-yl]pyrazole-4-carboxamide | 1558036-85-3 | MFCD31382019 | 99.6% | 431.49 | C24H25N5O3 | 50 MG
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Btk inhibitor 2 (BGB-3111 analog) is a small-molecule Bruton's tyrosine kinase (BTK) inhibitor described in patent US 20170224688 A1. Supplied for research use only, the compound is characterized by high purity and a molecular weight of 431.49 g/mol. It is offered as a solid powder and as a 10 mM solution in DMSO, and includes batch-specific certificate of analysis.
- High purity suitable for research applications (reported 99.57%).
- Molecular weight 431.49 g/mol.
- Available as solid and as 10 mM solution in DMSO.
- Provided with batch-specific certificate of analysis.
- Intended for in vitro and preclinical research use only.
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Medchemexpress LLC Zapalog | 1708091-24-0 | 99.6% | 1108.24 g·mol⁻¹ | C58H73N7O15 | 25MG
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Zapalog is a photocleavable small-molecule heterodimerizer used to reversibly control protein-protein interactions. It dimerizes proteins tagged with FKBP and DHFR domains and is cleaved by light to rapidly terminate interactions, enabling temporal control in chemical biology and optogenetics experiments.
- Photocleavable heterodimerizer allows rapid, reversible control of protein interactions.
- Compatible with FKBP and DHFR tagged proteins for inducible dimerization.
- Enables precise temporal control via light-induced photolysis.
- Supplied as a research-grade small molecule with high purity.
- Soluble in DMSO for preparation of working solutions.
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Medchemexpress LLC 2-[4-[(2S)-4-[(6-amino-3-pyridinyl)sulfonyl]-2-prop-1-ynylpiperazin-1-yl]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol | 1361224-53-4 | MFCD28386194 | 99.5% | 522.46 g/mol | C21H20F6N4O3S | 5MG
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AMG-3969 is a small-molecule research compound that disrupts the interaction between glucokinase (GK) and glucokinase regulatory protein (GKRP). It is supplied for research use in in vitro and in vivo studies and is reported to have potent activity against the GK-GKRP interaction.
- Disrupts GK-GKRP interaction; reported IC50 = 4 nM.
- High purity: 99.45% (supplier-reported).
- Molecular formula: C21H20F6N4O3S; molecular weight: 522.46 g/mol.
- Soluble in DMSO.
- Suitable for in vitro and in vivo research applications.
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Medchemexpress LLC Alliin | 556-27-4 | 177.22 | 1 ML
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Alliin is an orally active sulfoxide compound that can be isolated from garlic. It exhibits hypoglycemic, antioxidant, anti-inflammatory, and antitumor activities.
- Orally active compound.
- Can be isolated from garlic.
- Exhibits hypoglycemic activity.
- Exhibits antioxidant activity.
- Exhibits anti-inflammatory activity.
- Exhibits antitumor activity.
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Medchemexpress LLC Phospho-AMPK alpha 2(Ser345) Antibody (YA225) | Protein A affinity purified | 62 kDa | 50 UL
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Phospho-AMPK alpha 2(Ser345) Antibody (YA225) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-AMPK alpha 2(Ser345). It is for research use only.
- Host: Rabbit
- Clonality: Recombinant, monoclonal
- Species reactivity: Human, mouse
- Purity: Protein A affinity purified
- Conjugation: Non-conjugated
- Modification: Phosphorylated
- Isotype: IgG
- Appearance: Liquid
- Formulation: Supplied in 1*TBS (pH7.4), 0.05% BSA and 40% Glycerol. Preservative: 0.05% Sodium Azide.
- Storage & stability: Stored at -20°C for 1 year. Avoid repeated freeze/thaw cycles.
- Shipping: Shipped with blue ice.
- Subcellular localization: Cytoplasm; nucleus
- Immunogen: Synthetic phosphopeptide corresponding to residues surrounding Ser345 of Human AMPK alpha 2. AA range: 338-352.
- Gene ID: 5563 [NCBI]
- SwissProt ID: P54646
- RRID: AB_3102528
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eMolecules 165253-29-2 | 3-(Bromomethyl)tetrahydrofuran | Advanced ChemBlocks - In Stock | MFCD08234790 | 165.030 | C5H9BrO | 97.000 | BrCC1CCOC1 | 1g | 381411436
3-(Bromomethyl)tetrahydrofuran | Advanced ChemBlocks - In Stock | 165253-29-2 | MFCD08234790 | 165.030 | C5H9BrO | 97.000 | BrCC1CCOC1 | 1g | 381411436
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eMolecules 1678528-03-4 | [3-(HYDROXYMETHYL)BICYCLO[1.1.1]PENTAN-1-YL]METHANOL | AstaTech | MFCD24450308 | 128.171 | C7H12O2 | 95.000 | OCC12CC(CO)(C1)C2 | 0.1g | 771349933
[3-(HYDROXYMETHYL)BICYCLO[1.1.1]PENTAN-1-YL]METHANOL | AstaTech | 1678528-03-4 | MFCD24450308 | 128.171 | C7H12O2 | 95.000 | OCC12CC(CO)(C1)C2 | 0.1g | 771349933
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Medchemexpress LLC Goflikicept 1mg | 1mg
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Goflikicept (RPH 104) is a fusion protein that selectively binds and inactivates both circulating IL-1 and IL-1 Goflikicept has the potential for the research of ST-segment elevation myocardial infarction (STEMI)[1]
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Medchemexpress LLC LY223982 | 117423-74-2 | 99.7% | 502.56 | 1 ML
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LY223982 is a potent and specific inhibitor of the leukotriene B4 receptor. It effectively blocks the binding of [3H]LTB4 to its receptor with an IC50 of 13.2 nM. This compound also acts as a potent antagonist of human neutrophil aggregation induced by LTB4 and inhibits transient leukopenia in rabbits.
- Potent and specific inhibitor of leukotriene B4 receptor
- Inhibits [3H]LTB4 binding to LTB4 receptor (IC50: 13.2 nM)
- Antagonizes aggregation of human neutrophils by LTB4 (IC50: 100 nM)
- Inhibits transient leukopenia induced by LTB4 in rabbits (ED50: 3 mg/kg)
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Medchemexpress LLC 3-[5-bromo-6-[(2R,3R)-2-(4-fluorophenyl)-3-(hydroxymethyl)morpholine-4-carbonyl]-1-methylbenzimidazol | 2259620-80-7 | 98.9% | 616.48 g/mol | C31H27BrFN5O3 | 1 ML
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PDE12-IN-1 is a potent, selective inhibitor of phosphodiesterase 12 supplied as a 10 mM solution in DMSO (1 mL). It increases 2′,5′-linked adenylate polymers (2-5A) and has reported antiviral activity. Intended for laboratory research use only; not for human or clinical applications.
- Potent PDE12 inhibition (pIC50 = 9.1).
- Increases 2-5A levels (pEC50 = 7.7).
- Supplied as a 10 mM solution in DMSO, 1 mL vial.
- High purity (98.85%).
- Molecular formula C31H27BrFN5O3; molecular weight 616.48 g/mol.
- Store sealed, away from moisture and light; in solvent: -80°C up to 6 months, -20°C up to 1 month.
- For research use only; not for human use.
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